Publication date: Aug 31, 2023
In addition to acute hyperinflammatory responses, SARS-CoV-2 infections can have long-term effects on our immune system leading to, for example, post-acute sequelae of COVID-19 (PASC). In this issue of Cell, Cheong et al. show that severe infections via IL-6 induce persistent epigenetic signatures in hemopoietic stem cells and their myeloid progenitors associated with increased inflammatory potential.
| Concepts | Keywords |
|---|---|
| Covid | Acute |
| Hyperinflammatory | Addition |
| Innate | Covid |
| Myeloid | Haunting |
| Signatures | Hyperinflammatory |
| Immune | |
| Infections | |
| Innate | |
| Leading | |
| Long | |
| Memories | |
| Responses | |
| Sars | |
| System | |
| Term |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | COVID-19 |
| pathway | REACTOME | Immune System |
| disease | MESH | sequelae |
| disease | IDO | cell |
| disease | MESH | infections |
Original Article
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