Capture and inactivation of viral particles from bioaerosols by electrostatic precipitation.

Publication date: Sep 15, 2023

Infectious viral particles in bioaerosols generated during laparoscopic surgery place staff and patients at significant risk of infection and contributed to the postponement of countless surgical procedures during the COVID-19 pandemic causing excess deaths. The implementation of devices that inactivate viral particles from bioaerosols aid in preventing nosocomial viral spread. We evaluated whether electrostatic precipitation (EP) is effective in capturing and inactivating aerosolized enveloped and non-enveloped viruses. Using a closed-system model mimicking release of bioaerosols during laparoscopic surgery, known concentrations of each virus were aerosolized, exposed to EP and collected for analysis. We demonstrate that both enveloped and non-enveloped viral particles were efficiently captured and inactivated by EP, which was enhanced by increasing the voltage to 10 kV or using two discharge electrodes together at 8 kV. This study highlights EP as an effective means for capturing and inactivating viral particles in bioaerosols, which may enable continued surgical procedures during future pandemics.

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Concepts Keywords
10kv Particle Technology
Bioaerosols Virology


Type Source Name
disease VO inactivation
drug DRUGBANK Etoperidone
disease MESH infection
disease MESH COVID-19 pandemic
disease VO effective
disease VO Viruses
pathway REACTOME Release

Original Article

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