Preterm births prevalence during the COVID-19 pandemic in Brazil: results from the national database.

Publication date: Sep 04, 2023

The SARS-CoV-2 (COVID-19) pandemic impacted the health systems between and within countries, and in the course of the pandemic sexual and reproductive health services were the most disrupted. Findings from high-income settings have reported significant changes in preterm birth prevalence during the pandemic period. To understand the possible effects of the COVID-19 pandemic on preterm birth numbers at the Brazilian national level. We compare the number of preterm deliveries during the COVID-19 pandemic period (2020 and 2021) with previous years. We conducted a population-based cross-sectional study taking the period from January 2017 to December 2021 to account. We use individual-level live births data from the Brazilian Live Birth Information System (SINASC), and we estimate the odds ratio (OR) of preterm deliveries using propensity score weighting analysis in Brazil and its regions. During the study period (from 2017 to 2021), about 2. 7 million live births were recorded per year, and the missing value for gestational age at delivery was less than 1. 5%. The preterm birth prevalence slightly increased during the COVID-19 pandemic compared to the pre-pandemic period (11. 32% in 2021 vs 11. 09% in 2019, p-value 

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Concepts Keywords
Brazil Birth
December Births
Gestational Brazil
Pandemic Brazilian


Type Source Name
disease MESH Preterm births
disease MESH COVID-19 pandemic
disease VO population
disease MESH live births
drug DRUGBANK Coenzyme M
disease VO time
disease VO pregnant women
disease IDO country
disease MESH neonatal deaths
disease MESH infection
disease MESH stillbirths
disease MESH inflammation
drug DRUGBANK Methylergometrine
disease MESH pneumonia
drug DRUGBANK Esomeprazole
disease VO document
disease MESH aids
drug DRUGBANK Aspartame
disease MESH marital status
disease MESH multiple pregnancies
disease MESH anomalies
disease IDO quality
disease VO protocol
disease IDO process
disease MESH pregnancy outcomes
disease MESH Uncertainty
disease MESH miscarriage
disease MESH causality
disease MESH unemployment
disease MESH vector borne diseases
disease MESH fetal deaths
disease MESH abortion rates
disease MESH morbidity
drug DRUGBANK Isosorbide Mononitrate
drug DRUGBANK Trifluoro-thiamin phosphate
pathway REACTOME Reproduction
disease VO organization

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