Predictors of the post-COVID condition following mild SARS-CoV-2 infection.

Predictors of the post-COVID condition following mild SARS-CoV-2 infection.

Publication date: Sep 20, 2023

Whereas the nature of the post-COVID condition following mild acute COVID-19 is increasingly well described in the literature, knowledge of its risk factors, and whether it can be predicted, remains limited. This study, conducted in Norway, uses individual-level register data from 214,667 SARS-CoV-2 infected individuals covering a range of demographic, socioeconomic factors, as well as cause-specific healthcare utilization in the years prior to infection to assess the risk of post-COVID complaints ≥3 months after testing positive. We find that the risk of post-COVID was higher among individuals who prior to infection had been diagnosed with psychological (OR = 2. 12, 95% CI 1. 84-2. 44), respiratory (OR = 2. 03, 95% CI 1. 78-2. 32), or general and unspecified health problems (OR = 1. 78, 95% CI 1. 52-2. 09). To assess the predictability of post-COVID after mild initial disease, we use machine learning methods and find that pre-infection characteristics, combined with information on the SARS-CoV-2 virus type and vaccine status, to a considerable extent (AUC = 0. 79, 95% CI 0. 75-0. 81) could predict the occurrence of post-COVID complaints in our sample.

Open Access PDF

Concepts Keywords
Covid Assess
Healthcare Complaints
Norway Condition
Virus Cov


Type Source Name
disease MESH post-COVID condition
disease MESH SARS-CoV-2 infection
pathway REACTOME SARS-CoV-2 Infection
disease MESH infection
disease VO vaccine
disease VO report
drug DRUGBANK Flunarizine
disease MESH asthma
pathway KEGG Asthma
disease MESH obesity
drug DRUGBANK Coenzyme M
disease VO vaccination
disease VO vaccinated
disease VO unvaccinated
disease IDO symptom
disease IDO country
drug DRUGBANK Saquinavir
drug DRUGBANK Ranitidine
disease IDO history
disease VO population
disease MESH reinfection
drug DRUGBANK Nicorandil
disease VO Tax
disease MESH Communicable Diseases
disease MESH emergency
disease VO organization
disease IDO process
drug DRUGBANK Cysteamine
disease VO inefficient
drug DRUGBANK Adenosine
disease MESH complications
disease MESH coronavirus infection
disease MESH Multiple Sclerosis
disease MESH Neuroinflammation
disease MESH loneliness
drug DRUGBANK Fenamole
disease MESH syndrome
drug DRUGBANK Tromethamine
disease MESH chronic illness

Original Article

(Visited 1 times, 1 visits today)