Impact of SARS-CoV-2 infection in pregnant women and their babies: clinical and epidemiological features.

Publication date: Nov 25, 2023

Assess the risk associated with COVID-19 in pregnant women on maternal and neonatal outcomes in Catalonia (Spain) in 2020, before the beginning of COVID-19 vaccination campaign. Cross-sectional descriptive study with all pregnant women (41,560) and their live newborns (42,097) (1st March to 31st December 2020). Women were classified: positive and negative COVID-19 diagnosis during pregnancy. The outcomes analysed were complications during pregnancy, gestational age, admission of newborns to neonatal intensive care unit (NICU) and birth weight. Associations among positive COVID-19 and maternal and infant variables were measured with logistic regression models. Results were expressed as odds ratios and 95% confidence intervals. Models were adjusted for nationality, maternal age, socioeconomic status, type of pregnancy and type of centre where the delivery occurred (public or private management hospital). A total of 696 women (1. 7%) were diagnosed with COVID-19 during pregnancy. Women with COVID-19 were 4. 37 times more likely to have complications during pregnancy (4. 37; 3. 52-5. 40). A total of 713 newborns (1. 7%) were from mothers with COVID-19. A positive diagnosis of COVID-19 increased the risk of preterm birth (1. 41; 1. 03-1. 89), admission to NICU (1. 40; 1. 06-1. 82) and low birth weight (1. 35; 0. 99-1. 80) in babies. Pregnant women with COVID-19 had higher risk of developing complications during pregnancy and their newborns were more likely to be admitted to NICU and had prematurity.

Concepts Keywords
Hospital Complicaciones del embarazo
Pregnancy COVID-19
Socioeconomic Nacimiento prematuro
Pregnancy outcomes
Premature birth
ReciƩn nacido


Type Source Name
disease MESH SARS-CoV-2 infection
pathway REACTOME SARS-CoV-2 Infection
disease VO pregnant women
disease VO vaccination
disease MESH complications
disease MESH preterm birth
disease MESH Pregnancy outcomes

Original Article

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