Characteristics of SARS-CoV-2 reinfection with Omicron BA.2.75 subvariants in Thai Adults.

Publication date: Nov 26, 2023

Omicron subvariants of SARS-CoV-2 may resist vaccine- or infection-induced immunity thereby increasing the risk of reinfections in previously infected persons. This study aimed to investigate the clinical severity and the average time to the onset of Omicron reinfection. This survey study collected clinical data on Omicron reinfection. Information on time of infection, reinfection interval, overall clinical presentation, and severity of infection was reported. The total prevalence of symptoms among 201 participants was significantly higher in the first infection (risk difference (RD), 9.86%; 95% CI, 7.54-12.19]) compared to the second infection, and the hospitalization rate among all participants was significantly lower for the second infection than the primary infection (odds ratio (OR), 6.25; 95% CI, 2.158-24.71). The prevalence of symptoms compared with the first infection with pre-Omicron variants was similar to that of the first infection with the Omicron variant (RD, 2.56%; 95% CI, -6.14-1.01). However, the hospitalization rate for pre-Omicron primary infection was significantly higher (OR, 6.76; 95% CI, 2.87-15.87]) than that observed with Omicron variants. The severity of the primary infection and of a pre-Omicron variant was greater than that of a secondary infection or with an Omicron variant.

Concepts Keywords
Breastfeeding Ba
Chicago Clinical
Diabetes Infection
Thailand Infections
Medrxiv
Omicron
Participants
Pre
Preprint
Prevalence
Primary
Reinfection
Symptoms
Variant
Version

Semantics

Type Source Name
disease MESH reinfection
disease VO vaccine
disease MESH infection
disease VO time
disease IDO primary infection
disease MESH secondary infection
disease MESH Osteoarthritis
disease MESH COVID 19
disease VO organization
disease VO USA
disease VO vaccination
disease VO dose
disease IDO infection prevalence
disease MESH sore throat
disease VO nose
disease IDO production
disease IDO symptom
disease MESH pneumonia
disease MESH chest pain
disease MESH breakthrough infection
disease VO titer
disease VO population
disease IDO replication
disease VO unvaccinated
disease VO protocol
drug DRUGBANK Etoperidone
disease MESH COPD
disease MESH Hypertension
disease MESH Diabetes Mellitus
disease MESH Cardiovascular diseases
disease MESH Obesity
disease MESH Dyslipidemia
disease MESH Allergy
disease MESH Asthma
pathway KEGG Asthma
disease MESH gout
disease VO vaccine dose

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