Hydrogen Water: Extra Healthy or a Hoax?-A Systematic Review.

Hydrogen Water: Extra Healthy or a Hoax?-A Systematic Review.

Publication date: Jan 12, 2024

Hydrogen-rich water (HRW) has emerged as a novel approach in the field of health and wellness. It is believed to have therapeutic antioxidant properties that can neutralize harmful free radicals in the human body. It has also been shown to be beneficial in mitigating oxidative stress-induced damage through its anti-inflammatory and anti-apoptotic pathways. We aim to conduct a systematic review to evaluate the potential benefits of hydrogen-rich water. The review protocol was uploaded on PROSPERO. After the initial search criteria, the articles were reviewed by two blinded investigators, and a total of 25 articles were included in the systematic review. The potential benefits of hydrogen-rich water on various aspects of health, including exercise capacity, physical endurance, liver function, cardiovascular disease, mental health, COVID-19, oxidative stress, and anti-aging research, are a subject of growing interest and ongoing research. Although preliminary results in clinical trials and studies are encouraging, further research with larger sample sizes and rigorous methodologies is needed to substantiate these findings. Current research needs to fully explain the mechanisms behind the potential benefits of hydrogen-rich water. Continued scientific exploration will provide valuable insights into the potential of hydrogen-rich water as an adjunctive therapeutic approach in the future.

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Concepts Keywords
Future anti-apoptotic
Liver anti-inflammatory
Radicals antioxidant
Rich Deception
Therapeutic Health Status
hydrogen water
hydrogen-rich water
hydrogenated water
Mental Health


Type Source Name
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disease MESH COVID-19
disease VO USA
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disease MESH glucose intolerance
disease MESH hypertension
disease MESH atherosclerosis
disease MESH diabetes mellitus
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disease VO time
drug DRUGBANK Lactic Acid
disease IDO blood
disease VO efficiency
drug DRUGBANK Cefradine
disease MESH inflammation
disease IDO cell
disease MESH neurodegenerative diseases
pathway REACTOME Neurodegenerative Diseases
disease MESH acidosis
disease MESH lifestyle
drug DRUGBANK Oxygen
disease MESH allergy
disease MESH decompression sickness
disease IDO production
disease MESH hyperlipidemia
drug DRUGBANK Cholesterol
disease MESH metabolic syndrome
disease MESH unstable angina
disease MESH reactive hyperemia
drug DRUGBANK Fenamole
disease MESH emergency
drug DRUGBANK Nonoxynol-9
disease MESH infection
drug DRUGBANK Urea
drug DRUGBANK Nitrogen
disease MESH death
disease MESH cancer
drug DRUGBANK Fluorouracil
disease VO population
disease MESH panic disorder
disease MESH chronic hepatitis
disease MESH Hepatitis
disease MESH alcoholic fatty liver
disease MESH NAFLD
disease MESH Liver dysfunction
disease MESH heart disease
disease MESH bile
disease VO Glycoprotein
drug DRUGBANK Calcium
drug DRUGBANK Magnesium sulfate
disease VO volume
drug DRUGBANK Magnesium
disease MESH coronary artery disease
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disease MESH mood disorders
drug DRUGBANK Kava
drug DRUGBANK St. John’s Wort
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drug DRUGBANK Ginkgo biloba
disease MESH cognitive impairment
disease MESH anxiety disorder
disease MESH adjustment disorders
disease VO dose
drug DRUGBANK Zinc
drug DRUGBANK Selenium
disease VO study design
pathway KEGG Apoptosis
drug DRUGBANK Diethylstilbestrol
disease MESH clinical significance
disease VO effectiveness
drug DRUGBANK Isoxaflutole
pathway KEGG Cellular senescence
disease VO Pal
disease MESH overweight
disease MESH psychiatric disorders
drug DRUGBANK Bismuth subgallate
drug DRUGBANK Ubidecarenone

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