Alternations of antibiotic resistance genes and microbial community dynamics on shared bicycles before and after pandemic lockdown.

Alternations of antibiotic resistance genes and microbial community dynamics on shared bicycles before and after pandemic lockdown.

Publication date: Feb 25, 2024

The prevalence of shared bicycles has raised concerns over their potential to transmit pathogens and microbes harboring antibiotic resistance genes (ARGs), which pose significant human health risks. This study investigated the impact of anthropogenic activities on the composition of ARGs and microbial communities on shared bicycles during the COVID-19 pandemic and subsequent lockdown when shared bicycle usage was altered. A total of 600 swab samples from shared bicycle surfaces were collected in Shanghai before and during COVID-19 lockdown periods. Even during lockdown, 12 out of 14 initially detected ARG subtypes persisted, indicating their tenacity in the face of reduced anthropogenic activities. These ARGs displayed significantly higher absolute and relative abundance levels before the lockdown. In addition, the percentage of potential pathogens in the total microbial abundance remained at 0. 029 % during the lockdown, which was lower than the pre-lockdown percentage of 0. 035 % and suggested that these risks persist within shared bicycle systems. Interestingly, although microbial abundance decreased without the consecutive use of shared bicycles during lockdown, the microbial diversity increased under the impact of restricted anthropogenic activities (p

Concepts Keywords
Bicycles Antibiotic resistance genes
Pandemic COVID-19 lockdown
Shanghai Microbial community
Tenacity Shared bicycles
Therapy Surveillance

Semantics

Type Source Name
disease IDO antibiotic resistance
disease MESH COVID-19 pandemic
drug DRUGBANK L-Arginine

Original Article

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