Reproducibility and Repeatability of Intervoxel Incoherent Motion MRI Acquisition Methods in Liver.

Reproducibility and Repeatability of Intervoxel Incoherent Motion MRI Acquisition Methods in Liver.

Publication date: Jan 19, 2024

Intravoxel incoherent motion (IVIM) diffusion weighted MRI (DWI) has potential for evaluating hepatic fibrosis but image acquisition technique influence on diffusion parameter estimation bears investigation. To minimize variability and maximize repeatably in abdominal DWI in terms of IVIM parameter estimates. Prospective test-retest and image quality comparison. Healthy volunteers (3F/7M, 29. 9 +/- 12. 9 years) and Family Study subjects (18F/12M, 51. 7 +/- 16. 7 years), without and with liver steatosis. Abdominal single-shot echo-planar imaging (EPI) and simultaneous multi-slice (SMS) DWI sequences with respiratory triggering (RT), breath-holding (BH), and navigator echo (NE) at 3 Tesla. SMS-BH, EPI-NE, and SMS-RT data from twice-scanned healthy volunteers were analyzed using 6 cD7 b-values (0-800 s⋅mm ) and lower (LO) and higher (HI) b-value ranges. Family Study subjects were scanned using SMS and standard EPI sequences. The biexponential IVIM model was used to estimate fast-diffusion coefficient (D ), fraction of fast diffusion (f), and slow-diffusion coefficient (D ). Scan time, estimated signal-to-noise ratio (eSNR), eSNR per acquisition, and distortion ratio were compared. Coefficients of variation (CoV) and Bland Altman analyses were performed for test-retest repeatability. Interclass correlation coefficient (ICC) assessed interobserver agreement with P 

Concepts Keywords
9years diffusion
Hepatic fibrosis
Mri intervoxel incoherent motion
Tesla liver
Volunteers

Semantics

Type Source Name
disease MESH fibrosis
disease IDO quality
disease MESH liver steatosis
disease VO time

Original Article

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