The impact of obesity in hospitalized patients with COVID-19: a retrospective cohort study.

The impact of obesity in hospitalized patients with COVID-19: a retrospective cohort study.

Publication date: Jan 19, 2024

Obesity is believed to be a risk factor for COVID-19 and unfavorable outcomes, although data on this remains to be better elucidated. To evaluate the impact of obesity on the endpoints of patients hospitalized due to SARS-CoV-2. This retrospective cohort study evaluated patients hospitalized at a tertiary hospital (Hospital das ClcEDnicas da Faculdade de Medicina da USP) from March to December 2020. Only patients positive for COVID-19 (real-time PCR or serology) were included. Data were collected from medical records and included clinical and demographic information, weight and height, SAPS-3 score, comorbidities, and patient-centered outcomes (mortality, and need for mechanical ventilation, renal replacement therapy, or vasoactive drugs). Patients were divided into categories according to their BMI (underweight, eutrophic, overweight and obesity) for comparison porpoise. A total of 2547 patients were included. The mean age was 60. 3 years, 56. 2% were men, 65. 2% were white and the mean BMI was 28. 1 kg/m. SAPS-3 score was a risk factor for all patient-centered outcomes (HR 1. 032 for mortality, OR 1. 03 for dialysis, OR 1. 07 for vasoactive drug use, and OR 1. 08 for intubation, p 

Concepts Keywords
1kg COVID-19
December Critical care
Diabetol Mechanical ventilation
Obesity Mortality
Pcr Obesity

Semantics

Type Source Name
disease MESH obesity
disease MESH COVID-19
drug DRUGBANK Tropicamide
disease VO time
disease MESH underweight
disease MESH overweight

Original Article

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