COVID-19 managed on respiratory wards and intensive care units: Results from the national COVID-19 outcome report in Wales from March 2020 to December 2021.

COVID-19 managed on respiratory wards and intensive care units: Results from the national COVID-19 outcome report in Wales from March 2020 to December 2021.

Publication date: Jan 19, 2024

A COVID-19 hospital guideline was implemented across all 18 acute hospitals in Wales in March 2020, promoting ward management of COVID pneumonitis and data collected across the first 3 Waves of the pandemic (Wave 1 March 1st 2020 to November 1st 2020, Wave 2 November 2st 2020 to February 21st 2021 and Wave 3 June 1st 2021 to December 14th 2021). The aim of this paper is to compare outcomes for patients by admission setting and type of ventilatory support given, with a particular focus on CPAP therapy. This is a retrospective observational study of those aged over 18 admitted to hospital with community acquired COVID-19 between March 2020 and December 2021. The outcome of interest was in-hospital mortality. Univariate logistic regression models were used to compare crude outcomes across the waves. Multivariable logistic regression models were used to assess outcomes by different settings and treatments after adjusting for Wave, age, sex, co-morbidity and deprivation. Of the 7,803 records collected, 5,887 (75. 4%) met the inclusion criteria. Analysis of those cases identified statistically significant outcome improvements across the waves for all patients combined (Waves 1 to 3: 31. 5% to 18. 8%, p

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Concepts Keywords
December 1st
Hospitals Collected
Pandemic Compare
Wales Covid
December
Hospital
Logistic
March
November
Outcome
Outcomes
Regression
Wales
Wave
Waves

Semantics

Type Source Name
disease MESH COVID-19
disease VO report
disease MESH pneumonitis
disease MESH morbidity
drug DRUGBANK Methionine
disease MESH Infection
disease MESH Infectious Diseases
drug DRUGBANK Coenzyme M

Original Article

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