The prevalence of obstructive sleep apnea syndrome after COVID-19 infection.

The prevalence of obstructive sleep apnea syndrome after COVID-19 infection.

Publication date: Jan 01, 2024

Obstructive sleep apnea is a well-known risk factor regarding the severity of COVID-19 infection. However, to date, relatively little research performed on the prevalence of obstructive sleep apnea in COVID-19 survivors. The purpose of this study was to investigate the risk of obstructive sleep apnea after COVID-19 infection. This study was based on data collected from the US Collaborative Network in TriNetX. From January 1, 2020 to June 30, 2022, participants who underwent the SARS-CoV-2 test were included in the study. Based on their positive or negative results of the COVID-19 test results (the polymerase chain reaction [PCR] test), we divided the study population into two groups. The duration of follow-up began when the PCR test was administered and continued for 12 months. Hazard ratios (HRs) and 95% confidence intervals (CIs) for newly recorded COVID-19 positive subjects for obstructive sleep apnea were calculated using the Cox proportional hazards model and compared to those without COVID-19 infection. Subgroup analyses were performed for the age, sex, and race, groups. The COVID-19 group was associated with an increased risk of obstructive sleep apnea, at both 3 months of follow-up (HR: 1. 51, 95% CI: 1. 48-1. 54), and 1 year of follow-up (HR: 1. 57, 95% CI: 1. 55-1. 60). Kaplan-Meier curves regarding the risk of obstructive sleep apnea revealed a significant difference of probability between the two cohorts in the follow-up periods of 3 months and 1 year (Log-Rank test, p 

Concepts Keywords
Infection Cohort study
June COVID-19
Pcr COVID-19
Sleep Female
obstructive sleep apnea
Proportional Hazards Models
SARS-CoV-2 infection
Sleep Apnea, Obstructive


Type Source Name
disease MESH obstructive sleep apnea syndrome
disease MESH COVID-19
disease MESH infection
disease VO population
pathway REACTOME SARS-CoV-2 Infection

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