The Trend of Arrhythmias in Patients With COVID-19: A Complication or Late Manifestation?

The Trend of Arrhythmias in Patients With COVID-19: A Complication or Late Manifestation?

Publication date: Dec 01, 2023

Patients diagnosed with coronavirus disease (CVD) who experience cardiovascular complications or have pre-existing cardiovascular disease are at an increased risk of death. The primary heart-related consequences associated with COVID-19 encompass venous thromboembolism, shock, heart failure, arrhythmias, myocarditis, acute myocardial infarction, and acute cardiac damage. The coronavirus has the potential to induce cardiovascular complications or exacerbate pre-existing CVD through various mechanisms. These mechanisms include dysregulation of the renin-angiotensin-aldosterone system; direct viral toxicity; damage to endothelial cells; formation of blood clots and subsequent inflammation, a phenomenon known as thromboinflammation; an excessive immune response known as cytokine storm; and an imbalance between the demand and supply of oxygen in the body. In this study, we comprehensively analyze the cardiovascular symptoms, histology, and underlying mechanisms associated with COVID-19. Our aim is to contribute to the identification of future research objectives and aid in the advancement of therapeutic management approaches.

Concepts Keywords
Aldosterone ace2
Cardiac cardiovascular disease
Coronavirus covid-19
Late cytokine storm
Thromboembolism endothelial damage
type 2 myocardial infarction


Type Source Name
disease MESH COVID-19
pathway KEGG Coronavirus disease
disease MESH complications
disease MESH cardiovascular disease
disease MESH death
disease MESH venous thromboembolism
disease MESH shock
disease MESH heart failure
disease MESH myocarditis
disease MESH blood clots
disease MESH inflammation
disease MESH thromboinflammation
disease IDO immune response
disease MESH cytokine storm
drug DRUGBANK Oxygen
disease MESH myocardial infarction

Original Article

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