Long-Term Outcomes of Survivors of COVID-19 with Moderate to Severe Infection and Children with Multisystem Inflammatory Syndrome or MIS-C.

Long-Term Outcomes of Survivors of COVID-19 with Moderate to Severe Infection and Children with Multisystem Inflammatory Syndrome or MIS-C.

Publication date: Jan 20, 2024

The study aims to evaluate the long-term outcomes - functional, pulmonary and non-pulmonary (other organs) – in children hospitalized with COVID-19 infection or with Multisystem inflammatory syndrome (MIS-C) after 1-2 y of discharge. All children with moderate or severe COVID-19 or MIS-C were enrolled. Out of 45 enrolled subjects, 19. 8% had COVID-19 infection and 82% had MIS-C. Four children (8. 9%) had abnormal baseline echocardiography; two each with cardiac dysfunction and coronary dilatation. At baseline, 44% had moderate disability and 24% had mild disability as per Pediatric Cerebral Performance Category (PCPC). On follow-up, only 8. 9% (n = 4) had mild and 2. 2% (n = 1) had moderate disability as per the PCPC score. One child developed new onset tuberculosis of the bone. None had any pulmonary morbidities. Follow-up echocardiogram was also within normal limits for children with abnormal findings. Further studies in different populations (settings) are required to draw meaningful conclusions about long-term effects of COVID-19 on children.

Concepts Keywords
Bone Functional outcome
Echocardiography MIS-C
Pcpc Moderate COVID
Tuberculosis Non-pulmonary outcomes
Pulmonary outcomes
Severe COVID

Semantics

Type Source Name
disease MESH COVID-19
disease MESH Infection
disease MESH Syndrome
disease MESH tuberculosis
pathway KEGG Tuberculosis
disease MESH morbidities
disease MESH Long Covid

Original Article

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