An Exploratory Analysis of Contributors to Cognitive Functioning Among Sexual and Gender Minority Individuals Who Had COVID-19.

Publication date: Feb 02, 2024

Sexual and gender minority (SGM) individuals face mental health disparities. However, research analyzing SGM people’s mental health after a COVID-19 diagnosis is scarce. In this secondary analysis of a remote study, we 1) examined associations between cognitive and psychosocial health and 2) explored differences between these health outcomes among SGM (n = 14) and heterosexual cisgender (nā€‰=ā€‰64) U. S. adults who had COVID-19. We used the Patient Reported Outcome Measures Information System (PROMIS) v2. 0 to assess subjective cognition and the BrainCheck cognitive test to analyze objective cognition. We administered the Perceived Stress Scale and PROMIS 57 Profile V. 2.0 to measure psychosocial health. SGM COVID-19 survivors had worse scores in depression, anxiety, sleep disturbance, pain, stress, and objective cognition than heterosexual cisgender participants (p-values < .05). Objective cognition was associated with age, SGM classification, racial or ethnic minority classification, income, comorbidities, COVID-19 severity, number of symptoms, and pain (|0. 137| < r < |0. 373|, p-values < .05). Subjective cognition was associated with comorbidities, number of symptoms, depression, anxiety, sleep disturbance, pain, and stress (|0. 158| < r < |0. 537|, p-values < .05). Additional studies are needed to expand what is known about post-COVID-19 health disparities and to guide policies and interventions that promote cognitive functioning.

Concepts Keywords
Cisgender cognitive function
Heterosexual COVID-19
Psychosocial healthcare disparities
Sleep psychosocial functioning


Type Source Name
disease MESH COVID-19
disease MESH psychosocial functioning

Original Article

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