Recovery From Central Retinal Artery Occlusion Accompanying Paracentral Acute Middle Maculopathy After COVID-19 Vaccination.

Publication date: Jan 01, 2024

Although ocular complications following COVID-19 vaccination have been reported, particularly retinal vascular occlusion and uveitis, their definitive causal relationships remain uncertain. This report presents a case of central retinal artery occlusion (CRAO) with paracentral acute middle maculopathy (PAMM) developed one day after receiving Pfizer COVID-19 vaccine, with a favorable outcome. The patient experienced sudden vision loss in her left eye, and her vision dropped to hand motion the day after vaccination. The initial examination suggested CRAO, but optical coherence tomography (OCT) revealed PAMM. We administered intravenous d-mannitol and acetazolamide and performed ocular massage. Two days later, her corrected visual acuity improved to 0. 4, and further improvement to 1. 2 occurred after 16 days. To the best of our knowledge, no reports have documented CRAO with PAMM following mRNA COVID-19 vaccination. The relationship between COVID-19 vaccination and retinal vascular occlusion remains unknown, highlighting the need for further research.

Concepts Keywords
Acetazolamide covid-19
Maculopathy covid-19 vaccine
Massage mrna vaccine
Oct pfizer-biontech covid-19 vaccine
Vaccination retinal artery occlusion


Type Source Name
disease MESH Central Retinal Artery Occlusion
disease MESH Maculopathy
disease MESH COVID-19
disease VO vaccination
disease MESH complications
disease MESH uveitis
disease VO report
disease VO vaccine
drug DRUGBANK Mannitol
drug DRUGBANK Acetazolamide
disease VO COVID-19 vaccine

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