A Possible Case of Hypertensive Crisis With Aortic Dissection After an Anti-COVID-19 Vaccine.

Publication date: Feb 03, 2024

Aortic dissection, a potentially fatal event, usually presents with acute intense chest or back pain. Painless aortic dissections constitute about 10% of all cases. High blood pressure is a common finding in both painless and painful aortic dissections. During the coronavirus disease (COVID-19) pandemic, various anti-COVID vaccines have been massively used. Although these vaccines are generally safe, there is a small risk of adverse effects which are mostly mild and transient, but sometimes they could be life-threatening. We report a case of painless aortic dissection that occurred within minutes of receiving the COVID-19 inactivated vaccine. A 65-year-old woman with chronic controlled systemic hypertension developed slurred speech, decreased level of consciousness, generalized weakness, and dyspnea without chest, back, or abdominal pain a few minutes after receiving the second dose of inactivated COVID-19 vaccine; she had a systolic blood pressure of 220 mmHg and left-sided pleural effusion. Drainage of the pleural effusion revealed gross blood and a spiral chest and mediastinum CT with intravenous contrast showed a penetrating atherosclerotic ulcer in the descending aorta. Therefore, thoracic endovascular aortic repair (TEVAR) was carried out, and the patient was discharged in satisfactory condition after 3 days.

Concepts Keywords
220mmhg aneurysm
3days aorta
Coronavirus COVID-19
Hypertension dissecting
Painless effusion


Type Source Name
disease MESH Aortic Dissection
disease VO COVID-19 vaccine
disease MESH back pain
disease MESH High blood pressure
pathway KEGG Coronavirus disease
disease MESH COVID-19
disease VO report
disease VO COVID-19 inactivated vaccine
disease VO dose
disease IDO blood
disease MESH pleural effusion
disease MESH penetrating atherosclerotic ulcer
disease MESH aneurysm

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