The impact of the COVID-19 pandemic on alcohol use disorder symptoms: Testing interactions with polygenic risk.

Publication date: Feb 08, 2024

Objective: The purpose of this study was to test whether COVID impact interacts with genetic risk (polygenic risk score/PRS) to predict alcohol use disorder (AUD) symptoms. Method: Participants were n = 455 college students (79. 6% female, 51% European Ancestry/EA, 24% African Ancestry/AFR, 25% Americas Ancestry/AMER) from a longitudinal study during the initial stage (March-May 2020) of the pandemic. Path models allowed for the examination of PRS and previously identified COVID-19 impact constructs. Results: There was a main effect of the AUD PRS on AUD symptoms within the EA group (β: .165, p 

Concepts Keywords
Alcohol college students
Genetic COVID-19
Pandemic genetic risk
Therapy pandemic
substance use


Type Source Name
disease MESH COVID-19 pandemic
disease MESH alcohol use disorder
disease MESH substance use

Original Article

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