Incidence and risk factors of peripheral nerve injuries 3 months after ICU discharge: a retrospective study comparing COVID-19 and non-COVID-19 critically ill survivors.

Publication date: Feb 09, 2024

Peripheral nerve injuries (PNI) have been associated with prone positioning (PP) in mechanically ventilated (MV) patients with COVID-19 pneumonia. The aims of this retrospective study were to describe PNI prevalence 3 months (M3) after intensive care unit (ICU) discharge, whether patients survived COVID-19 or another critical illness, and to search for risk factors of PNI. A total of 55 COVID (62 [54-69] years) and 22 non-COVID (61. 5 [48-71. 5] years) patients were followed at M3, after an ICU stay of respectively 15 [9-26. 5] and 13. 5 [10-19. 8] days. PNI symptoms were reported by 23/55 (42. 6%) COVID-19 and 8/22 (36%) non-COVID-19 patients (p = 0. 798). As the incidence of PNI was similar in both groups, the entire population was used to determine risk factors. The MV duration predicted PNI occurrence (OR (CI95%) = 1. 05 (1. 01-1. 10), p = 0. 028), but not the ICU length of stay, glucocorticoids, or inflammation biomarkers. In the present cohort, PNI symptoms were reported in at least one-third of the ICU survivors, in similar proportion whether patients suffered from severe COVID-19 or not.

Concepts Keywords
3months COVID-19
Biomarkers Critical illness
Pneumonia Follow-up clinic
Peripheral nerve injury


Type Source Name
disease MESH COVID-19
disease MESH critically ill
disease MESH pneumonia
disease VO population
disease MESH inflammation

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