Pregnant Patients with COVID-19 Admitted to an ICU: A Comparison with a Historical Cohort of Critical Pregnant Patients without COVID-19.

Publication date: Jan 23, 2024

Maternal mortality and ICU admissions have increased during the COVID-19 pandemic. We reported a case-series of pregnant patients with COVID-19 admitted to an ICU and we compared them with a historical cohort of pregnant patients admitted to an ICU without COVID-19. We included all pregnant patients with laboratory-confirmed COVID-19 infection admitted to our ICU in 2021. As a historical control group, we included all pregnant women who were admitted to our ICU between 1 January 2008 and 31 December 2013. In 2021, 11 pregnant patients (pts) with COVID-19 were admitted to an ICU, representing 2. 87% of ICU admissions. We found that pregnant patients with COVID-19 (1) had a higher BMI (34. 6 vs. 28. 8, p = 0. 04) and a lower gestational age (30. 6 vs. 34 weeks, p = 0. 03), (2) were mainly admitted for respiratory failure (100% vs. 2. 7%; p = 0. 001) and (3) required more days of invasive and non-invasive ventilations (54. 5% vs. 5. 2%, p = 0. 002), a longer duration of stay at the ICU (21. 9 vs. 4. 8 days, p < 0. 0001) and had a higher mortality rate (27. 3% vs. 0%, p = 0. 0192). Pregnant patients with COVID-19 represent a challenge for ICU physicians due to their different characteristics and outcomes when compared to pregnant patients without COVID-19.

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Concepts Keywords
December COVID-19
Laboratory ICU
Pandemic maternal mortality


Type Source Name
disease MESH COVID-19
disease MESH infection
disease VO pregnant women
disease MESH respiratory failure
drug DRUGBANK Coenzyme M
disease MESH pregnancy outcomes
disease MESH complications
disease MESH maternal deaths
disease MESH live births
disease VO unvaccinated
disease MESH overweight
disease MESH comorbidity
disease IDO facility
disease VO protocol
drug DRUGBANK Acetylsalicylic acid
disease VO USA
disease VO ANOVA
disease MESH hemorrhage
disease MESH sepsis

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