The impact of SARS-Cov-2 Omicron infection on short-term outcomes after elective surgery in patients with gastrointestinal cancer.

Publication date: Mar 04, 2024

With the emergence of novel variants, Omicron variant caused a different clinical picture than the previous variants and little evidence was reported regarding perioperative outcomes after Omicron variants. The aim of the study was to evaluate the postoperative outcomes of gastrointestinal cancer patients following Omicron variants infection and also to determine the timing of surgery after infection recovery. A total of 124 patients who underwent gastrointestinal cancer surgery with prior SARS-CoV-2 infection between December 2022 and February 2023 were retrospectively reviewed. 174 cases underwent the same operation during December 2018 and February 2019 as control group. SARS-CoV-2-infected patients were further categorized into three groups based on infected time (1-3 weeks; 4-6 weeks; and ≥ 7 weeks). 90. 3% of SARS-CoV-2-infected patients had mild symptoms. The COVID-19 vaccination rate was 71. 0%, with a full vaccination rate of 48. 4%. There were no significant differences in 30-day morbidity and mortality. There was also no significant difference in pulmonary complications, cardiovascular complications, and surgical complications between the three different diagnosis time groups. In conclusion, reducing waiting time for elective surgery was safe for gastrointestinal cancer patients in the context of an increased transmissibility and milder illness severity with Omicron variant.

Concepts Keywords
6weeks Elective surgery
Cancer Gastrointestinal cancer
Gastrointestinal Postoperative complications
Postoperative SARS-CoV-2


Type Source Name
disease MESH infection
disease MESH gastrointestinal cancer
disease MESH SARS-CoV-2 infection
pathway REACTOME SARS-CoV-2 Infection
disease VO time
disease VO vaccination
disease MESH morbidity
disease MESH complications
disease MESH Postoperative complications

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