Temporal evolution of chest radiographic appearances in COVID-19 with clinicoradiological associations: a multicentre United Kingdom resident-led study.

Publication date: Apr 01, 2024

To describe the (a) frequency of improving, static, and worsening chest radiograph (CXR) appearances; (b) differences in demographic, initial rudimentary haematological and CXR variables and these patterns; and (c) frequency of different trajectories of serial CXR evolution, in COVID-19 patients presenting consecutively. This multicentre retrospective study included all COVID-19 patients admitted from 1-30 April 2020, meeting the inclusion criteria across 24 (blinded) hospitals. Follow-up CXRs on admission, the subsequent (where available), and at 4-8 weeks were scored for the presence of parenchymal opacities across six zones. Three cohorts were defined: improved, static, and/or worsened. The chi-squared and Kruskal-Wallis tests were used to compare demographic, laboratory, and CXR variables. Trajectories of CXR evolution were assessed when all three CXRs were available (226 patients). Of 452 included patients (median age 66 years, interquartile range 54. 3-79, 262 men), 211 (46. 7%) improved, 140 (31%) were static, and 101 (22. 3%) worsened. Improving patients were more likely younger, with a classic COVID-19 radiograph and higher initial CXR zonal severity scores (both p

Concepts Keywords
Clinicoradiological Appearances
Covid Chest
Demographic Covid
Worsening Cxr
Demographic
Evolution
Frequency
Improving
Included
Initial
Multicentre
Radiograph
Static
Trajectories
Variables

Semantics

Type Source Name
disease MESH COVID-19
disease VO frequency

Original Article

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