COVID-19 Severity in People With HIV Compared With Those Without HIV.

Publication date: Apr 15, 2024

People with HIV (PWH) may be at risk for more severe COVID-19 outcomes. We compared risk for severe COVID-19 in PWH with matched individuals without HIV. We identified adults in Massachusetts with a positive SARS-CoV-2 test, March 2020-July 2022, using electronic medical record data from 3 large clinical practice groups. We then used regression models to compare outcomes among PWH versus propensity score-matched people without HIV (matched 20:1) for severe COVID-19 (pneumonia or acute respiratory distress syndrome), hospitalization, and hospital length of stay. We identified 171,058 individuals with COVID-19; among them, 768 PWH were matched to 15,360 individuals without HIV. Overall, severe COVID-19 and hospitalization were similar in PWH and those without HIV (severe COVID-19: 3. 8% vs 3. 0%, adjusted odds ratio [OR] 1. 27, 95% confidence interval [CI]: 0. 86-1. 87; hospitalization: 12. 1% vs 11. 3%, adjusted OR: 1. 08, 95% CI: 0. 87 to 1. 35). Compared with people without HIV, PWH with low CD4 T-cell counts (

Concepts Keywords
Cd4 Adjusted
Hiv Adults
July Ci
Massachusetts Compared
Covid
Hiv
Hospitalization
Identified
Individuals
Matched
Outcomes
Pwh
Risk
Severe
Severity

Semantics

Type Source Name
disease MESH COVID-19
disease MESH pneumonia
disease MESH acute respiratory distress syndrome
disease IDO cell

Original Article

(Visited 1 times, 1 visits today)