Confinement tonicity on epidemic spreading.

Confinement tonicity on epidemic spreading.

Publication date: Mar 22, 2024

Emerging and re-emerging pathogens are latent threats in our society with the risk of killing millions of people worldwide, without forgetting the severe economic and educational backlogs. From COVID-19, we learned that self isolation and quarantine restrictions (confinement) were the main way of protection till availability of vaccines. However, abrupt lifting of social confinement would result in new waves of new infection cases and high death tolls. Here, inspired by how an extracellular solution can make water move into or out of a cell through osmosis, we define confinement tonicity. This can serve as a standalone measurement for the net direction and magnitude of flows between the confined and deconfined susceptible compartments. Numerical results offer insights on the effects of easing quarantine restrictions.

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Concepts Keywords
Covid Confinement
Economic Epidemic
Epidemic Epidemic final size
Killing Stability
Math

Semantics

Type Source Name
disease MESH COVID-19
disease MESH infection
disease MESH death
drug DRUGBANK Water
disease IDO cell
disease IDO history
disease MESH Black Death
disease MESH influenza
disease VO USA
disease VO population
drug DRUGBANK Guanosine
disease VO effective
disease VO Gap
disease IDO host
disease IDO pathogen
pathway REACTOME Reproduction
disease VO dead
disease IDO susceptible population
disease IDO infected population
disease VO time
drug DRUGBANK Aspartame
drug DRUGBANK L-Glutamine
disease VO vein
disease MESH uncertainty
disease MESH acute disease
drug DRUGBANK Vildagliptin
drug DRUGBANK Trifluridine
disease VO viable
disease MESH viral infection
disease IDO immune response
disease IDO country
drug DRUGBANK Morpholinylmercaptobenzothiazole
disease MESH infectious diseases
drug DRUGBANK Serine
disease IDO infectious disease
disease MESH pneumonia

Original Article

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