Otologic disease trends in Japan post-COVID-19 outbreak: A retrospective time-series analysis.

Otologic disease trends in Japan post-COVID-19 outbreak: A retrospective time-series analysis.

Publication date: Mar 23, 2024

To evaluate the potential impact of coronavirus disease 2019 (COVID-19) and vaccinations on otologic diseases, including facial nerve paralysis (including Ramsay Hunt syndrome), vestibular neuritis, sudden sensorineural hearing loss, and Meniere’s disease. In this retrospective study, we conducted a time-series analysis employing a causal impact algorithm on a large-scale inpatient database in Japan. We compared the actual number of hospitalized patients with otologic diseases to two predictions: one without any covariates and another with a covariate accounting for the reduction in the number of hospitalized patients due to lockdown measures. Additionally, we performed Granger causality tests to ensure the robustness of our findings. No significant increase was noted in the number of hospitalized patients with otologic diseases following the onset of the COVID-19 pandemic in the causal impact analysis. Similarly, no notable surge was observed in hospitalizations for these diseases following the introduction of the COVID-19 vaccine. The Granger causality tests results aligned with the causal impact analysis findings. Our findings indicate that COVID-19 and vaccinations had minimal discernible effects on hospitalization of patients with otologic diseases, suggesting that otologic diseases may not be significantly impacted by COVID-19 and vaccinations, which could have implications for public health policies and the allocation of healthcare resources during a pandemic. Further research and monitoring of long-term effects are warranted to validate these findings and guide healthcare decision-making.

Concepts Keywords
Coronavirus COVID 19
Covid Herpes zoster
Hospitalization Ramsay Hunt syndrome
Japan Time series analysis
Minimal Vaccine

Semantics

Type Source Name
disease MESH Otologic disease
disease MESH COVID-19
disease VO time
disease MESH Ramsay Hunt syndrome
disease MESH vestibular neuritis
disease MESH sensorineural hearing loss
disease MESH Meniere’s disease
disease IDO algorithm
disease MESH causality
disease VO COVID-19 vaccine
disease MESH Long Covid
disease MESH Herpes zoster
disease VO vaccine

Original Article

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