Dysphagia in patients with severe COVID-19: a retrospective study.

Publication date: Mar 21, 2024

To investigate dysphagia after extubation in patients with severe coronavirus disease 2019 (COVID-19). We retrospectively examined patients with severe COVID-19 treated in our hospital between August 2021 and March 2022. Feeding outcomes were categorized into two groups-(1) total oral intake, and (2) difficulty in oral intake. To assess the feeding outcome, we used modified water-swallowing test (MWST) for all patients. However, in cases where aspiration or recurrent laryngeal nerve palsy was suspected, we conducted the fiberoptic endoscopic evaluation of swallowing after MWST. Patient data were collected from medical records. Forty-six patients with severe COVID-19 were included. Among the 46 patients, 14 (30. 4%) experienced difficulties with oral intake. Older age, longer length of hospitalization, duration of mechanical ventilation, tracheostomy, diabetes, and higher serum levels of C-reactive protein (CRP) and procalcitonin (PCT) at the time of intubation were associated with difficulty in oral intake. The rate of difficulty with oral intake in patients with severe COVID-19 was 30. 4%, which is not as high as reported in previous studies. Older age, longer duration of mechanical ventilation, tracheostomy, diabetes, and higher levels of CRP and PCT were associated with the prevalence of oral intake difficulty, suggesting that early attention should be paid to high-risk patients who have preexisting deterioration of swallowing function due to aging and comorbidities, or who have prolonged intubation or tracheostomy to prevent aspiration pneumonia.

Open Access PDF

Concepts Keywords
August Dysphagia
Coronavirus Intubation
Diabetes SARS-CoV-2
Feeding Swallowing function
Tracheostomy Tracheostomy


Type Source Name
disease MESH Dysphagia
disease MESH COVID-19
drug DRUGBANK Water
disease MESH recurrent laryngeal nerve palsy
disease VO time
disease MESH aspiration pneumonia
drug DRUGBANK Coenzyme M
disease MESH severe acute respiratory syndrome
disease MESH sore throat
disease MESH acute respiratory distress syndrome
disease MESH infections
disease IDO infection
drug DRUGBANK Gold
disease VO vaccination
disease MESH Emergency
disease MESH complications
disease MESH hypertension
disease MESH dyslipidemia
drug DRUGBANK Creatine
disease VO USA
drug DRUGBANK Pentaerythritol tetranitrate
disease MESH encephalomyelitis
disease MESH encephalopathy
disease MESH peripheral neuropathy
disease MESH gastroesophageal reflux
drug DRUGBANK Medical air
disease MESH disuse atrophy
disease MESH pulmonary fibrosis
disease MESH tachypnea
disease MESH interstitial pneumonia
disease MESH myositis
disease MESH autoimmunity
disease MESH bacterial infections
disease MESH inflammation
disease MESH pneumonia
disease MESH dysphonia
disease IDO site
disease MESH stroke
disease MESH chronic obstructive pulmonary disease
pathway REACTOME Reproduction

Original Article

(Visited 1 times, 1 visits today)