Understanding Low Vaccine Uptake in the Context of Public Health in High-Income Countries: A Scoping Review.

Understanding Low Vaccine Uptake in the Context of Public Health in High-Income Countries: A Scoping Review.

Publication date: Mar 04, 2024

Although the COVID-19 pandemic has caused the need for the largest mass vaccination campaign ever undertaken to date, African, Caribbean, and Black (ACB) populations have shown both a disproportionately high degree of negative impacts from the pandemic and the lowest willingness to become vaccinated. This scoping review aims to investigate low vaccine uptake in ACB populations relative to public health in high-income countries. A search was conducted in MEDLINE(R) ALL (OvidSP), Embase (OvidSP), CINAHL (EBSCOHost), APA PsycInfo (OvidSP), the Cochrane Central Register of Controlled Trials (OvidSP), the Cochrane Database of Systematic Reviews (OvidSP), the Allied and Complimentary Medicine Database (Ovid SP), and the Web of Science following the Joanna Briggs Institute (JBI) framework for scoping reviews, supplemented by PRISMA-ScR. Theoretical underpinnings of the intersectionality approach were also used to help interpret the complexities of health inequities in the ACB population. The eligibility criteria were based on the population, concept, context (PCC) framework, and publications from 2020-19 July 2022 which discussed vaccine uptake amongst ACB people in high-income countries were included. Analysis was carried out through thematic mapping and produced four main themes: (1) racism and inequities, (2) sentiments and behaviors, (3) knowledge and communication, and (4) engagement and influence. This study has contributed to the identification and definition of the issue of low vaccine uptake in ACB populations and has illustrated the complexity of the problems, as vaccine access is hampered by knowledge, psychological, socioeconomic, and organizational barriers at the individual, organizational, and systemic levels, leading to structural inequities that have manifested as low vaccine uptake.

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Concepts Keywords
Caribbean African
Complimentary Black and Caribbean
Racism COVID-19 vaccination
Vaccinated high-income countries
vaccine hesitancy
vaccine uptake


Type Source Name
disease VO vaccine
disease MESH COVID-19 pandemic
disease VO vaccination
disease VO vaccinated
disease VO Apa
disease VO population
drug DRUGBANK Factor IX Complex (Human)
disease VO Canada
disease MESH infections
disease MESH death
drug DRUGBANK Coenzyme M
disease IDO infection
disease MESH influenza
disease VO organization
disease MESH uncertainty
drug DRUGBANK Spinosad
disease MESH severe acute respiratory syndrome
disease MESH Middle East respiratory syndrome
disease VO unvaccinated
drug DRUGBANK Pentaerythritol tetranitrate
disease MESH infectious diseases
disease MESH smallpox
disease MESH rabies
disease MESH polio
disease MESH plague
disease MESH typhoid
disease VO protocol
drug DRUGBANK Methionine
disease VO effective
disease IDO country
disease VO volume
disease IDO process
disease IDO intervention
disease VO publication
disease VO USA
disease VO vaccine efficacy
disease VO human papillomavirus vaccine
disease VO mouth
disease MESH violence
pathway REACTOME Immune System
disease VO dose
disease MESH low socioeconomic status
disease MESH housing insecurity
disease VO time
disease VO immunization
disease MESH heart failure
disease VO frequency
disease MESH contraindication
disease VO effectiveness
disease MESH coronary artery disease
disease MESH diabetes mellitus
disease MESH hypertension
disease MESH re infection
disease IDO susceptibility
disease MESH Pneumonia
disease MESH pneumococcal disease
disease IDO history
disease MESH syphilis
disease VO pregnant women
disease VO Equity
disease MESH educational attainment
disease IDO production
disease MESH morbidities
disease VO ReCOV
drug DRUGBANK Trestolone
drug DRUGBANK Nonoxynol-9
disease VO ineffective
disease MESH burnout
disease VO Gap
disease MESH causes
disease MESH emergency
disease VO vaccine approval process
disease IDO pathogen
disease VO vaccination coverage
disease IDO object
disease VO report
disease VO coronavirus vaccine
drug DRUGBANK Tropicamide
disease VO vaccine dose
drug DRUGBANK Delorazepam
drug DRUGBANK Amlodipine
disease VO Papillomavirus vaccine
disease MESH Systemic Lupus Erythematosus
pathway KEGG Systemic lupus erythematosus
disease MESH Lifestyle

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