The impact of long term COVID-19 infection on the patients’ erectile function and on anxiety and on depression as well as the impact of daily tadalafil 5 mg supplementation in patients with erectile dysfunction.

Publication date: Mar 29, 2024

The study examined the impact of long term COVID-19 infection on the patients’ erectile function and anxiety and depression in the same patients as well as the impact of daily tadalafil 5 mg supplementation on their erectile function. Recovered 114 men were evaluated by the validated Arabic version of the international index of erectile function (ArIIEF-5) and the Arabic versions of the patient health questionnaire-9 (PHQ-9) and the generalized anxiety disorder-7 (GAD-7) at time of presentation, at 3 months and at 6 months, respectively. Forty recovered patients who still complained of ED received tadalafil 5 mg daily for 2 months then were evaluated again at 3 and 6 months by penile duplex, the Arabic versions of the patient health questionnaire-9 (PHQ-9) and the generalized anxiety disorder-7 (GAD-7) at the same periods, respectively. At the time of presentation, there was a positive correlation between the severity of COVID-19 infection, ArIIEF-5 and PHQ-9 (r = 0. 249, p = 0. 008; r = 0. 241, p = 0. 010, respectively). Most of the patients showed normal penile duplex parameters. There were 40 ED patients at presentation, 5 ED patients at 3 months and 3 ED patients at 6 months, respectively. ED in COVID-19 patients who were not suffering from chronic illnesses before the affection, is primarily psychological and completely responsive to tadalafil.

Concepts Keywords
6months ED
Anxiety GAD-7
Daily Long term COVID-19
Men PHQ-9
Urologia Tadalafil 5 mg

Semantics

Type Source Name
disease MESH COVID-19
disease MESH infection
drug DRUGBANK Tadalafil
disease MESH erectile dysfunction
disease MESH anxiety disorder
disease VO time
disease MESH chronic illnesses
disease MESH Long Covid

Original Article

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