Invasive group A streptococcal infection can be fatal to pregnant women in restricted medical resources remote areas-Emergent alert after COVID-19 pandemic.

Publication date: Apr 01, 2024

Invasive group A streptococcal (iGAS) infection is a leading cause of maternal death. The increase in the number of patients with iGAS in Japan is markedly greater than before the coronavirus pandemic. We encountered a case of iGAS infection, on a remote island with restricted medical resources, in a third-trimester pregnant woman, resulting in both maternal and fetal death. A 34-year-old woman was admitted via a local general hospital with a high fever. Intrauterine fetal death disseminated intravascular coagulation, and septic shock were confirmed. Broad-spectrum antibiotics were started, and the patient was returned to the local general hospital. Eight hours after arrival, the patient died of circulatory and respiratory dysfunction complications. iGAS infections in remote areas may directly lead to life-threatening conditions and should be treated as an emergency, comparable to the serious conditions of placental abruption or placenta previa.

Concepts Keywords
Coronavirus group A streptococcal
Japan perinatal
Old pregnant
Pandemic remote area
Pregnant septic shock


Type Source Name
disease MESH group A streptococcal infection
disease VO pregnant women
disease MESH COVID-19 pandemic
disease MESH infection
disease MESH maternal death
disease MESH fetal death
disease MESH disseminated intravascular coagulation
disease MESH septic shock
disease MESH complications
disease MESH emergency
disease MESH placental abruption
disease MESH placenta previa

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