Publication date: Jun 30, 2024
Vaccines are used for the control of infectious diseases of animals. Over other types of vaccinations like live attenuated or killed vaccines, mRNA-based vaccines have significant advantages. As only a small portion of the pathogen’s genetic material is employed and the dose rate of mRNA-based vaccines is low, there is the least possibility that the pathogen will reverse itself. A carrier or vehicle that shields mRNA-based vaccines from the host’s cellular RNases is necessary for their delivery. mRNA vaccines have been shown to be effective and to induce both a cell-mediated immune response and a humoral immune response in clinical trials against various infectious diseases (viral and parasitic) affecting the animals, including rabies, foot and mouth disease, toxoplasmosis, Zikavirus, leishmaniasis, and COVID-19. The current review aims to highlight the use of mRNA-based vaccines both in viral and parasitic diseases of animals.
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | infectious diseases |
| disease | IDO | pathogen |
| disease | VO | dose |
| disease | IDO | host |
| disease | VO | effective |
| disease | IDO | humoral immune response |
| disease | MESH | rabies |
| disease | MESH | foot and mouth disease |
| disease | MESH | toxoplasmosis |
| pathway | KEGG | Toxoplasmosis |
| disease | MESH | leishmaniasis |
| pathway | KEGG | Leishmaniasis |
| disease | MESH | COVID-19 |
| disease | MESH | parasitic diseases |
| disease | VO | vaccine |
| disease | MESH | Virus Diseases |