Safety and effectiveness of remdesivir in hospitalized patients with COVID-19 and severe renal impairment: experience at a large medical center.

Safety and effectiveness of remdesivir in hospitalized patients with COVID-19 and severe renal impairment: experience at a large medical center.

Publication date: Dec 01, 2024

Literature on the safety of remdesivir in hospitalized COVID-19 patients with severe renal impairment is limited. We aimed to investigate the safety and effectiveness of remdesivir in this population. We conducted a retrospective cohort study of adult hospitalized COVID-19 patients who received remdesivir between April 2022 and October 2022. Outcomes were compared between estimated glomerular filtration rate (eGFR)

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Concepts Keywords
April Acute Kidney Injury
Covid acute kidney injury
Hospitalized Adenosine Monophosphate
October Adenosine Monophosphate
Renal Adult
Aged
Alanine
Alanine
Antiviral Agents
Antiviral Agents
Bradycardia
COVID-19
COVID-19
COVID-19 Drug Treatment
Female
Glomerular Filtration Rate
Hospital Mortality
Hospitalization
Humans
Male
Middle Aged
remdesivir
remdesivir
Renal Insufficiency
Retrospective Studies
SARS-CoV-2
severe renal impairment
Treatment Outcome

Semantics

Type Source Name
disease VO effectiveness
disease MESH COVID-19
disease VO population
disease MESH Acute Kidney Injury
drug DRUGBANK Adenosine phosphate
drug DRUGBANK L-Alanine
disease MESH Bradycardia
disease MESH Renal Insufficiency

Original Article

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