Publication date: Jul 10, 2024
The recent COVID-19 pandemic has raised interest in efficient air disinfection solutions. The application of germicidal ultraviolet (GUV) irradiation is an excellent contender to prevent airborne transmission of COVID-19, as well as other existing and future infectious airborne diseases. While GUV has already been proven effective in inactivating SARS-CoV-2, quantitative data on UV susceptibility and dose requirements, needed to predict and optimize the performance of GUV solutions, is still limited. In this study, the UV susceptibility of aerosolized SARS-CoV-2 to 254 nm ultraviolet (UV) irradiation is investigated. This is done by employing 3D computational fluid dynamics based simulations of SARS-CoV-2 inactivation in a test chamber equipped with an upper-room UV-C luminaire and comparing the results to previously published measurements performed in the same test chamber. The UV susceptibility found in this study is (0. 6 +/- 0. 2) m/J, which is equivalent to a D dose between 3 and 6 J/m. These values are in the same range as previous estimations based on other corona viruses and inactivation data reported in literature.
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| Concepts | Keywords |
|---|---|
| Covid | Aerosols |
| Efficient | Aerosols |
| Future | Computer Simulation |
| Pandemic | COVID-19 |
| Viruses | Disinfection |
| Humans | |
| Hydrodynamics | |
| SARS-CoV-2 | |
| Ultraviolet Rays | |
| Virus Inactivation |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | IDO | susceptibility |
| disease | MESH | COVID-19 pandemic |
| disease | VO | efficient |
| drug | DRUGBANK | Medical air |
| disease | VO | effective |
| disease | VO | dose |
| disease | VO | inactivation |
| disease | VO | Viruses |
| drug | DRUGBANK | Coenzyme M |
| disease | MESH | infection |
| disease | MESH | infectious diseases |
| disease | IDO | pathogen |
| disease | VO | time |
| disease | IDO | process |
| disease | IDO | facility |
| drug | DRUGBANK | Acetylcholine |
| drug | DRUGBANK | Albendazole |
| disease | MESH | uncertainty |
| disease | VO | volume |
| drug | DRUGBANK | Aspartame |
| disease | VO | manufacturer |
| drug | DRUGBANK | Water |
| disease | VO | mouth |
| disease | IDO | history |
| disease | VO | effectiveness |
| disease | MESH | crimean congo haemorrhagic fever |
| drug | DRUGBANK | Methylene blue |
| disease | IDO | replication |
| disease | VO | device |
| disease | VO | report |
| disease | VO | Env |
| disease | VO | Bacteria |
| disease | VO | efficiency |