Epidemiology of candidemia during COVID-19 pandemic era in a teaching hospital: a non-concurrent cohort study.

Epidemiology of candidemia during COVID-19 pandemic era in a teaching hospital: a non-concurrent cohort study.

Publication date: Jul 10, 2024

During the COVID-19 pandemic, an increase in the incidence of bloodstream infections caused by fungi of the Candida genus, also known as candidemia, was observed in patients with SARS-CoV-2 infection. This study aimed to assess the incidence of candidemia, the factors related to COVID-19-associated candidemia (CAC), and prognostic factors. A non-concurrent cohort of 87 cases of patients aged over 18 years with candidemia between March 2020 and February 2022 was evaluated. Incidence density (ID) was calculated by the number of patient-days during the period. All causes of mortality within 30 days of observation were considered. Logistic regression and Cox Proportional Hazards Regression were used, respectively, to determine factors associated with CAC and prognostic factors. Values less than 0. 05 were considered significant. The ID of CAC was eight times higher than candidemia in patients without COVID-19 [2. 40 per 1,000 person-days vs. 0. 27 per 1,000 person-days; p

Concepts Keywords
Fungi candidemia
Hospital COVID-19
Pandemic incidence
Teaching mortality

Semantics

Type Source Name
disease MESH candidemia
disease MESH COVID-19 pandemic
disease MESH bloodstream infections
disease VO Fungi
pathway REACTOME SARS-CoV-2 Infection
disease MESH causes

Original Article

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