Risk factors and outcome of acute kidney injury in critically ill patients with SARS-CoV-2 pneumonia: a multicenter study.

Risk factors and outcome of acute kidney injury in critically ill patients with SARS-CoV-2 pneumonia: a multicenter study.

Publication date: Jul 12, 2024

To assess incidence, risk factors and impact of acute kidney injury(AKI) within 48 h of intensive care unit(ICU) admission on ICU mortality in patients with SARS-CoV-2 pneumonia. To assess ICU mortality and risk factors for continuous renal replacement therapy (CRRT) in AKI I and II patients. Retrospective observational study. Sixty-seven ICU from Spain, Andorra, Ireland. 5399 patients March 2020 to April 2022. Demographic variables, comorbidities, laboratory data (worst values) during the first two days of ICU admission to generate a logistic regression model describing independent risk factors for AKI and ICU mortality. AKI was defined according to current international guidelines (kidney disease improving global outcomes, KDIGO). Of 5399 patients included 1879 (34. 8%) developed AKI. These patients had higher ICU mortality and AKI was independently associated with a higher ICU mortality (HR 1. 32 CI 1. 17-1. 48; p

Concepts Keywords
Ireland Acute kidney injury
Kidney Insuficiencia renal aguda
Laboratory Intensive care unit
Pneumonia SARS-CoV-2 pneumonia

Semantics

Type Source Name
disease MESH acute kidney injury
disease MESH critically ill
disease MESH pneumonia
disease MESH kidney disease

Original Article

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