Publication date: Jul 15, 2024
We investigated if children with Long Covid (n=14) have activated platelets compared with healthy controls (n=14). Platelet activation and secretion markers were investigated by flow cytometry using MoAbs directed against P-selectin, CD63, and PAC-1 in quiescent platelets and in platelets stimulated with 10-uM adenosine diphosphate and 25-uM protease activated receptor 1-activating peptide. Circulating platelets of patients with Long Covid had significantly increased expression of the activation marker cytometry using MoAbs directed against P-selectin (P = 0. 019).
| Concepts | Keywords |
|---|---|
| Adenosine | Activated |
| Covid | Activation |
| Cytometry | Case |
| Increased | Circulating |
| Platelets | Covid |
| Cytometry | |
| Directed | |
| Investigated | |
| Long | |
| Moabs | |
| N=14 | |
| Platelets | |
| Selectin |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | Long Covid |
| pathway | KEGG | Platelet activation |
| drug | DRUGBANK | PAC-1 |
| drug | DRUGBANK | Adenosine |
Original Article
(Visited 2 times, 1 visits today)