Circulating white blood cell traits and prolonged night shifts: a cross-sectional study based on nurses in Guangxi.

Publication date: Jul 24, 2024

This study aimed to elucidate the effects of long day and night shifts on immune cells in a population of nurses. This cross-sectional study in December 2019 was based on a group of nurses. 1568 physically healthy caregivers were included, including 1540 women and 28 men. 1093 nurses had long-term shift work (working in a rotating system for > 1 year). The receiver operating characteristic curve, Ensemble Learning, and Logistic regression analyses were used to evaluate factors related to long-term shift work. The night shift group nurses had significantly higher MPV, PLCR, and WBC and significantly lower BASO%, ELR, MCHC, PLR, RDW-CV, and RDW-SD (P

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Concepts	Keywords
Blood	Adult
December	China
Healthy	Circadian rhythm
Nurses	COVID-19
Wbc	Cross-Sectional Studies
	Eosinophil-to-lymphocyte ratio
	Female
	Humans
	Leukocyte Count
	Leukocytes
	Male
	Middle Aged
	Nurses
	Nurses
	Shift work
	Shift Work Schedule
	WBC
	Work Schedule Tolerance

Semantics

Type	Source	Name
disease	IDO	blood
disease	IDO	cell
disease	VO	population
drug	DRUGBANK	Coenzyme M
disease	IDO	immune population
drug	DRUGBANK	Saquinavir
disease	MESH	COVID 19
disease	MESH	tumorigenesis
disease	MESH	breast cancer
pathway	KEGG	Breast cancer
pathway	KEGG	Circadian rhythm
disease	VO	volume
drug	DRUGBANK	Methacholine
drug	DRUGBANK	Flunarizine
disease	MESH	jet lag
disease	MESH	sleep disorders
disease	MESH	mood disorders
disease	VO	time
pathway	REACTOME	Immune System
disease	IDO	susceptibility
disease	MESH	infections
disease	VO	effective
disease	MESH	viral infections
disease	IDO	adaptive immune response
disease	VO	Viruses
disease	MESH	tumor
disease	MESH	abnormalities
disease	MESH	obesity
drug	DRUGBANK	Etoperidone
drug	DRUGBANK	Methionine
disease	MESH	hypertension
disease	MESH	hyperlipidemia
disease	MESH	hyperglycemia
disease	MESH	hematologic diseases
disease	MESH	autoimmune diseases
disease	MESH	parasitic diseases
disease	MESH	psychiatric disorders
disease	MESH	inflammation
drug	DRUGBANK	Ranitidine
disease	IDO	algorithm
disease	IDO	intervention
disease	IDO	process
disease	VO	frequency
disease	VO	organization
disease	VO	leukocyte
drug	DRUGBANK	Pentaerythritol tetranitrate
drug	DRUGBANK	Proline
disease	VO	age
disease	MESH	chronic diseases
disease	MESH	cardiovascular disease
disease	MESH	lymphomas
drug	DRUGBANK	Iron
drug	DRUGBANK	Nonoxynol-9
drug	DRUGBANK	Isoxaflutole
disease	VO	report
disease	MESH	atherosclerosis
disease	MESH	stroke
disease	MESH	metabolic syndrome
disease	MESH	sleep deprivation
disease	VO	organ
disease	MESH	myocardial infarction
disease	MESH	insomnia
drug	DRUGBANK	Lithium cation
disease	MESH	Allergy
disease	MESH	pneumonia
disease	MESH	endometrial cancer
pathway	KEGG	Endometrial cancer
drug	DRUGBANK	Guanosine
disease	MESH	acute lymphoblastic leukemia
drug	DRUGBANK	Hyaluronic acid

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