Mortality Rates of the Spanish Flu and Coronavirus Disease 2019 in the Netherlands: A Historical Comparison.

Publication date: Jul 25, 2024

The coronavirus disease 2019 (COVID-19) pandemic has been called the deadliest disease event in history. In this study, we compared the cause-specific mortality rate of the Spanish flu (1918-1920) with that of COVID-19 (2020-2022) in the Netherlands. During the periods of exposure, about 50 000 people died of COVID-19 and 32 000 people of the Spanish flu. In absolute numbers, COVID-19 seems to be deadlier than Spanish flu. However, the crude mortality rates for COVID-19 and Spanish flu were 287 and 486 per 100 000 inhabitants, respectively. Comparing age-standardized mortality rates, there would have been 28 COVID-19- and 194 Spanish flu-related deaths in 1918-1920, or 214 Spanish flu- and 98 COVID-19-related deaths in 2020-2022 per 100 000 inhabitants per year. Thus, taking the population differences into account, the Spanish flu would have been deadlier than COVID-19.

Concepts Keywords
Deadlier Adolescent
Flu Adult
Spanish Aged
Aged, 80 and over
cause of death
Child
Child, Preschool
COVID-19
COVID-19
epidemiology
Female
History, 20th Century
History, 21st Century
Humans
Infant
Influenza Pandemic, 1918-1919
Influenza, Human
Male
Middle Aged
mortality
Netherlands
Pandemics
SARS-CoV-2
Spanish flu
Young Adult

Semantics

Type Source Name
disease MESH Coronavirus Disease 2019
disease IDO history
disease VO population
disease MESH Long Covid
disease MESH cause of death
disease MESH Influenza

Original Article

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