Publication date: Aug 01, 2024
This systematic review and meta-analysis aimed to determine the efficacy of inhaled corticosteroids (ICS) on mortality in patients with coronavirus disease-2019 (COVID-19). A systematic search was made of PubMed, Embase, Cochrane Library, and clinicaltrials. gov, without language restrictions. Randomized controlled trials (RCTs) on the treatment of COVID-19 with ICS were reviewed. Studies were pooled to risk ratios (RRs), with 95% confidence intervals (CIs). Eleven RCTs (enrolling 5832 participants) met the inclusion criteria. There was no statistically significant difference in COVID-19-related death (RR 0. 88, 95% CI 0. 38-2. 04), all-cause death (RR 1. 05, 95% CI 0. 49-2. 23), and invasive ventilation (RR 1. 26, 95% CI 0. 60-2. 62) between the two groups. ICS was not associated with reduced mortality and invasive ventilation in patients with COVID-19.
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | COVID-19 |
| pathway | KEGG | Coronavirus disease |
| drug | DRUGBANK | Methionine |
| disease | MESH | death |
| disease | MESH | Long Covid |