Publication date: Jul 30, 2024
Measurement of corneal endothelial cells is critical for postoperative evaluation of phakic intraocular lens (pIOL) surgery. However, inter-instrument differences in corneal endothelial cell density (ECD) after pIOL implantation have not yet been reported. This study aimed to compare automated corneal endothelial cell analysis between CellChek-20 (Konan Medical, Hyogo, Japan) and EM-4000 (Tomey, Nagoya, Japan) in healthy and postoperative eyes with pIOL. We retrospectively analyzed 154 healthy and 236 postoperative eyes after pIOL surgery. Endothelial cell measurements were performed using CellChek-20 and EM-4000 with autofocusing and automated image analysis. ECD, percentage of hexagonal cells (HEX), coefficient of variation in cell size (CoV), and central corneal thickness (CCT) were compared between the two devices. The ECDs of the two devices were highly correlated in both healthy (Spearman’s correlation coefficient [r] = 0. 805; p
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| Concepts | Keywords |
|---|---|
| Healthy | Comparison |
| Japan | Corneal endothelial cell |
| Postoperative | Endothelial cell density |
| Spearman | Phakic intraocular lens |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | IDO | cell |
| drug | DRUGBANK | Coenzyme M |
| drug | DRUGBANK | Esomeprazole |
| disease | MESH | inflammation |
| drug | DRUGBANK | Trestolone |
| disease | VO | manufacturer |
| disease | IDO | history |
| drug | DRUGBANK | Celecoxib |
| disease | MESH | corneal opacity |
| disease | MESH | angle closure glaucoma |
| disease | VO | USA |
| drug | DRUGBANK | Indoleacetic acid |
| disease | IDO | algorithm |
| disease | VO | effective |
| disease | VO | company |
| disease | MESH | Cataract |
| drug | DRUGBANK | Clozapine |
| disease | MESH | myopia |
| disease | MESH | lens dislocation |
| disease | MESH | aphakia |
| disease | MESH | complications |
| disease | MESH | gout |
| disease | MESH | Fuchs endothelial corneal dystrophy |
| disease | MESH | glaucoma |
| disease | VO | protocol |