Publication date: Jul 30, 2024
Image credit: Shuo YangAlthough this research was conducted in flies and mice, the team believes similar processes can happen in humans. IL-6 activates a biochemical pathway called JAK-STAT in muscles, and there are already a number of approved drugs that can block this pathway. In each of these diseases, the brain can be exposed to inflammatory proteins that lead to a buildup of reactive oxygen species. The ones on the left are from healthy muscles, while the ones on the right are from muscles exposed to IL-6.
| Concepts | Keywords |
|---|---|
| Alzheimers | Advertisement |
| Biochemical | Alzheimers |
| Mice | Brain |
| Purple | Covid |
| Viral | Fatigue |
| Flies | |
| Hope | |
| Il | |
| Infection | |
| Inflammation | |
| Johnson | |
| Long | |
| Muscle | |
| Muscles | |
| Symptoms |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | muscle fatigue |
| disease | MESH | inflammation |
| disease | MESH | Long COVID |
| disease | MESH | syndromes |
| disease | MESH | complications |
| disease | MESH | infection |
| disease | VO | Bacteria |
| pathway | REACTOME | Immune System |
| disease | IDO | acute infection |
| disease | MESH | COVID-19 |
| disease | IDO | process |
| drug | DRUGBANK | Tropicamide |
| disease | MESH | rheumatoid arthritis |
| pathway | KEGG | Rheumatoid arthritis |
| disease | VO | population |
Original Article
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