Publication date: Jul 29, 2024

Ground glass nodules featured lung cancer have been identified in some teenagers in recent years. This study aims to investigate the characteristics and surgical outcomes of these patients and explore proper management strategy. Patients aged ≤20 with incidentally diagnosed lung cancer were retrospectively reviewed from February 2016 to March 2023. Based on lymph node evaluation status, these patients were divided into non-lymph node evaluation and lymph node evaluation groups. The clinical and pathological characteristics were analyzed. A total of 139 teenage patients were included, with an obviously increased cases observed from 2019, corresponding to the COVID-19 pandemic. The median age of the 139 patients was 18 years (range 12-20). 85 patients had pure ground glass nodules while others had mixed ground glass nodules. The mean diameter of nodules was 8. 87 +/- 2. 20 mm. Most of the patients underwent wedge resection (64%) or segmentectomy (31. 7%). 52 patients underwent lymph node sampling or dissection. None of these patients had lymph node metastasis. The majority of lesions were adenocarcinoma in situ (63 cases) and minimally invasive adenocarcinoma (72 cases), while 4 lesions were invasive adenocarcinoma. The median follow-up time was 2. 46 years, and none of these patients experienced recurrence or death during follow-up. The lymph node evaluation group had longer hospital stays (p 

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