[Severe cholecystitis during the COVID-19 pandemic : Influence of the COVID-19 pandemic on the frequency of surgery and outcome for elective and emergency cholecystectomy: a monocentric retrospective cohort analysis].

Publication date: Aug 01, 2024

With the outbreak of the COVID-19 pandemic medical care focused on management of the infectious event. Elective interventions were cancelled and the general advice was to stay at home. How this impacted urgent and elective cholecystectomies is the subject of this work. Urgent and elective cholecystectomy patients during the first year of the pandemic were compared with those of the previous year. The primary endpoint was the frequency of surgery. Furthermore, the American Society of Anesthesiologists (ASA) score, symptom duration until presentation as well as until surgery, preoperative inflammatory parameters, imaging, positive Murphy’s sign, type and duration of surgery, intraoperative drain placement, intraoperative and histological severity, need for and duration of postoperative antibiotic therapy, intensive care stay, length of stay and occurrence of postoperative complications were recorded. During the pandemic patients were sicker (ASA 2. 13 vs. 2. 31; p = 0. 039), the operating time was prolonged (64. 4 min vs. 74. 9 min; p = 0. 001) and patients were more likely to have concomitant peritonitis (15. 4% vs. 29. 1%: p = 0. 007). Furthermore, there was a trend in the presence of leukocytosis, a positive Murphy’s sign, intraoperative drain placement, intraoperative severity of inflammation, duration of postoperative antibiotic therapy and complication rate. During the COVID-19 pandemic cholecystitis presented with more pronounced inflammation, the surgical conditions were more difficult and postoperative recovery was prolonged.

Concepts Keywords
American Adult
Antibiotic Aged
Cancelled Aged, 80 and over
Cholecystectomy Cholecystectomy
Retrospective Cholecystectomy
Cholecystitis
Cholecystitis
Cohort Studies
COVID-19
Elective Surgical Procedures
Emergencies
Female
Germany
Humans
Length of Stay
Male
Middle Aged
Pandemics
Perioperative period
Postoperative Complications
Retrospective Studies
SARS-CoV-2
SARS-CoV‑2
Surgery
Treatment Outcome

Semantics

Type Source Name
disease MESH cholecystitis
disease MESH COVID-19 pandemic
disease VO frequency
disease MESH emergency
drug DRUGBANK Acetylsalicylic acid
disease IDO symptom
disease MESH postoperative complications
disease VO time
disease MESH peritonitis
disease MESH leukocytosis
disease MESH inflammation

Original Article

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