Publication date: Jul 30, 2024
Humoral immune responses after BNT162b2 vaccination are predominantly composed of immunoglobulin (Ig) G1 and IgG3 subclass antibodies. As previously described in adults, S1-specific and receptor-binding domain-specific IgG4 levels increase significantly 1 year after the second BNT162b2 vaccination in children 5-11 years of age. Understanding mRNA vaccine-specific IgG4 responses in all age groups is crucial as more mRNA vaccines will reach licensure in the coming years.
| Concepts | Keywords |
|---|---|
| Adults | Antibodies |
| Bnt162b2 | Bnt162b2 |
| Mrna | Cov |
| Spike | Delayed |
| Vaccines | Igg4 |
| Induction | |
| Mrna | |
| Noninflammatory | |
| Sars | |
| Specific | |
| Spike | |
| Vaccination | |
| Vaccines | |
| Year | |
| Years |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | VO | vaccination |
| disease | VO | vaccine |
Original Article
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