Effect of vaccinations and school restrictions on the spread of COVID-19 in different age groups in Germany.

Publication date: Dec 01, 2024

With the emergence of SARS-CoV-2, various non-pharmaceutical interventions were adopted to control virus transmission, including school closures. Subsequently, the introduction of vaccines mitigated not only disease severity but also the spread of SARS-CoV-2. This study leveraged an adapted SIR model and non-linear mixed-effects modeling to quantify the impact of remote learning, school holidays, the emergence of Variants of Concern (VOCs), and the role of vaccinations in controlling SARS-CoV-2 spread across 16 German federal states with an age-stratified approach. Findings highlight a significant inverse correlation (Spearman’s ρ = -0. 92, p

Concepts Keywords
Covid Age
Germany COVID-19
Learning Mathematical modeling
Spearman Non-pharmaceutical interventions
Vaccinations Vaccination

Semantics

Type Source Name
disease MESH COVID-19
disease VO age
disease VO vaccination

Original Article

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