Characteristics of medically attended influenza infection across age groups before the COVID-19 pandemic in Lebanon.

Publication date: Sep 01, 2024

Influenza represents a significant global health burden for individuals and society. This study assessed the burden of medically attended influenza at a tertiary medical center in Lebanon to describe the demographics, risk factors, and outcomes prior to the COVID-19 pandemic. This was a retrospective review of patients who tested positive for the influenza virus during three seasons between July 1, 2016 to June 30, 2019, at the American University of Beirut Medical Center. A total of 2049 patients who tested positive for influenza were analyzed. Influenza A accounted for 79. 6 % of cases, and influenza B for 19. 7 %, with influenza activity starting in October/November and peaking in December/January. Older age above 65 years (AOR=3. 584), obesity (AOR=2. 183), and chronic conditions such as chronic lung diseases (AOR=1. 832), and bacterial co-infection (AOR= 2. 834) were found to be independent risk factors for developing complications. Viral co-infection increased the likelihood of death tenfold. Vaccinated patients had a shorter mean hospital stay duration and a lower intensive care unit admission rate. The burden of medically attended influenza at our tertiary medical center in Lebanon prior to the COVID-19 pandemic was high. Vaccination decreased the likelihood of complications leading to intensive care unit admission in patients at risk.

Concepts Keywords
December Adolescent
Influenza Adult
June Age Factors
Vaccinated Aged
Aged, 80 and over
Burden
Child
Child, Preschool
Coinfection
COVID-19
COVID-19 pandemic
Female
Hospitalization
Humans
Infant
Influenza
Influenza A virus
Influenza B virus
Influenza, Human
Lebanon
Lebanon
Male
Middle Aged
Retrospective Studies
Risk Factors
SARS-CoV-2
Seasonality
Tertiary Care Centers
Vaccination
Young Adult

Semantics

Type Source Name
pathway REACTOME Influenza Infection
disease MESH COVID-19 pandemic
disease MESH Influenza
pathway KEGG Influenza A
disease MESH obesity
disease MESH chronic conditions
disease MESH lung diseases
disease MESH co-infection
disease MESH complications
disease MESH death
disease VO vaccinated
disease VO vaccination
disease VO adult age
drug DRUGBANK Influenza A virus
drug DRUGBANK Influenza B virus

Original Article

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