Radiation Recall Pneumonitis: Imaging Appearance and Differential Considerations.

Publication date: Sep 01, 2024

Radiation recall pneumonitis is an inflammatory reaction of previously radiated lung parenchyma triggered by systemic pharmacological agents (such as chemotherapy and immunotherapy) or vaccination. Patients present with non-specific symptoms such as cough, shortness of breath, or hypoxia soon after the initiation of medication or vaccination. Careful assessment of the patient’s history, including the thoracic radiation treatment plan and timing of the initiation of the triggering agent, in conjunction with CT findings, contribute to the diagnosis. Once a diagnosis is established, treatment includes cessation of the causative medication and/or initiation of steroid therapy. Differentiating this relatively rare entity from other common post-therapeutic complications in oncology patients, such as recurrent malignancy, infection, or medication-induced pneumonitis, is essential for guiding downstream clinical management.

Concepts Keywords
Chemotherapy Chemotherapy complication
Essential COVID-19-related complications
Korean Diagnosis, Differential
Thoracic Humans
Vaccination Immunotherapy
Lung
Radiation Pneumonitis
Radiation therapy
Radiation-induced pneumonitis
Tomography, X-Ray Computed

Semantics

Type Source Name
disease MESH Pneumonitis
disease VO vaccination
disease IDO history
disease IDO entity
disease MESH complications
disease MESH malignancy
disease MESH infection
disease MESH COVID-19

Original Article

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