Comprehensive assessment of corneal microstructural changes following V4c implantable collamer lens surgery using in vivo confocal microscopy.

Comprehensive assessment of corneal microstructural changes following V4c implantable collamer lens surgery using in vivo confocal microscopy.

Publication date: Sep 19, 2024

Implantable Collamer Lense (ICL) presents a viable alternative to conventional refractive surgeries, but their impact on corneal microstructure remains unclear. By employing in vivo confocal microscopy (IVCM), we examined changes in stromal and endothelial cells following the insertion of V4c ICLs, with the goal of enhancing post-surgical care and outcomes. In this longitudinal investigation, we conducted detailed preoperative assessments on 103 eyes from 53 participants. Follow-up evaluations were carried out after surgery at set intervals: one day, one week, one month, three months, six months, and twelve months. We used IVCM to analyze changes in stromal and endothelial cells. To assess differences between pre- and post-surgery variables and to investigate correlations with age, axial length (AL), and spherical equivalent refraction (SER), we applied a repeated measures mixed-effects model, with statistical significance set at P 

Open Access PDF

Concepts Keywords
Month Confocal microscopy
Refraction Endothelial cell density
Surgery Implantable collamer lens
V4c Myopia correction
Vivo Refractive surgery

Semantics

Type Source Name
drug DRUGBANK Serine
pathway REACTOME Reproduction
drug DRUGBANK Coenzyme M
disease MESH complications
drug DRUGBANK Esomeprazole
disease IDO quality
disease MESH lens opacities
disease MESH fibrosis
disease MESH refractive error
disease MESH ocular infections
disease MESH inflammations
disease IDO history
disease MESH hypersensitivities
disease MESH corneal diseases
disease MESH Myopia
drug DRUGBANK Oxybuprocaine
drug DRUGBANK Medical air
disease IDO object
drug DRUGBANK Cysteamine
drug DRUGBANK Aspartame
disease MESH glaucoma
disease MESH keratoconus
disease IDO cell

Original Article

(Visited 1 times, 1 visits today)