Publication date: Oct 01, 2024

To describe the impact on maternal and perinatal outcomes of the Delta variant of COVID-19 compared to the pre-Delta period in pregnant women with COVID-19 infections in one large public, non-profit hospital system. We conducted a retrospective chart review of identified COVID-19 diagnosed pregnant women with the outcome of pregnancy (livebirth or stillbirths). We assessed maternal and perinatal outcomes between the pre-delta and Delta variant time periods. A study cohort of 173 mother-baby dyads was identified from January 2020 to November 2021. Maternal outcomes showed a higher rate of cesarean section (33. 8%,49%; p = 0. 047), with a higher frequency for worsening maternal condition due to COVID-19 (2. 8%, 13. 7%; p = 0. 016) and association with non-reassuring fetal heart tones as indications for cesarean Sect. (53. 8%, 95%; p = 0. 008) during the Delta time period. There were more preterm births (16. 9%, 32. 4%; p = 0. 023) even when excluding stillbirths (16. 9%,30%; p = 0. 05). Cesarean section due to “worsening maternal condition” was an independent risk factors for early delivery (β = 2. 66, 93. 32-62. 02, p 

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