Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID (REVERSE-LC)

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In Long Covid News.

Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID (REVERSE-LC)

Publication date: Oct 04, 2024

The overarching goal of this study is to determine if baricitinib, as compared to placebo, will improve neurocognitive function, along with measures of physical function, quality of life, post-exertional malaise, effect of breathlessness on daily activities, post-COVID-19 symptom burden, and biomarkers of inflammation and viral measures, in participants with Long COVID.

Concepts Keywords
Childbearing COVID-19
Immunocompromised Long COVID
Pneumonia

Semantics

Type Source Name
drug DRUGBANK Baricitinib
disease MESH Long COVID
disease IDO quality
disease MESH breathlessness
disease MESH COVID-19
disease MESH symptom burden
disease MESH inflammation
pathway REACTOME SARS-CoV-2 Infection
disease IDO symptom
disease MESH brain fog
disease MESH dysautonomia
disease MESH postural orthostatic tachycardia syndrome
disease MESH chest pain
disease MESH fainting
disease MESH joint pain
disease MESH hair loss
disease MESH Cognitive impairment
disease MESH infection
disease MESH sore throat
disease MESH taste disorder
disease MESH pneumonia
disease MESH Acute Respiratory Distress Syndrome
disease MESH syphilis
disease IDO history
disease MESH Suicide
disease MESH allergic reactions
drug DRUGBANK Probenecid
disease MESH Venous thromboembolism
disease MESH thrombosis
disease MESH Malignancy
disease MESH lymphoproliferative disorder
disease MESH melanoma
pathway KEGG Melanoma
disease MESH skin cancers
drug DRUGBANK Alkaline Phosphatase
drug DRUGBANK Cholesterol
drug DRUGBANK Hepatitis B Vaccine (Recombinant)
disease MESH Hepatitis B
pathway KEGG Hepatitis B
disease MESH Hepatitis C
pathway KEGG Hepatitis C
disease MESH herpes zoster
disease MESH herpes simplex
disease MESH encephalitis
disease MESH latent tuberculosis infection
drug DRUGBANK Gold
disease MESH tuberculosis
pathway KEGG Tuberculosis
drug DRUGBANK p-Phenylenediamine
drug DRUGBANK BCG vaccine
disease MESH sepsis
disease MESH parasitic infection
disease IDO assay
disease IDO intervention
disease MESH viremia
disease MESH Infection|Coronavirus

Original Article

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