Exploring the Linkages Among Chronic Illness, Substance Use, and COVID-19 Infection in Adults Aged 50 Years and Older: Retrospective Cross-Sectional Analysis of National Representative Data.

Exploring the Linkages Among Chronic Illness, Substance Use, and COVID-19 Infection in Adults Aged 50 Years and Older: Retrospective Cross-Sectional Analysis of National Representative Data.

Publication date: Oct 15, 2024

The co-occurrence of chronic illnesses and substance use presents complex challenges for health care systems. Understanding the interplay between these factors, compounded by the context of the COVID-19 pandemic, is essential for effective intervention strategies. This study aims to investigate the relationships among chronic illness, substance use, and COVID-19 infection in adults aged 50 years and older. Participants were 1196 adults aged 50 years and older. Descriptive statistics were used to describe demographic information. Logistic regressions and multiple regression analyses were used to determine associations between chronic illnesses, substance use, and COVID-19 infection. Mediation analysis was used to determine the effect of chronic illness mediators in the association between COVID-19 concerns and substance use. The mean age was 68 (SD 10. 3) years, with 58. 6% (701/1196) being women. Adjusted analysis revealed that age and sex (women) significantly predicted a lower level of substance use (P

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Concepts Keywords
Covid Aged
Pandemic Aged, 80 and over
Retrospective Chronic Disease
Women co-occurring conditions
Comorbidity
COVID-19
COVID-19
Cross-Sectional Studies
Female
geriatrics
gerontology
Humans
Male
medical complexity
Middle Aged
multiple chronic conditions
older adults
Retrospective Studies
SARS-CoV-2
substance use
Substance-Related Disorders
United States

Semantics

Type Source Name
disease MESH Chronic Illness
disease MESH Substance Use
disease MESH COVID-19
disease MESH Infection
disease IDO intervention
drug DRUGBANK Coenzyme M
drug DRUGBANK substance P
disease MESH Comorbidity
disease MESH multiple chronic conditions

Original Article

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